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Article

Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.

American journal of respiratory and critical care medicine - 15 Mar 2009

Sohn Myung Hyun, Lee Ji Hyun, Kim Kyung Won, Kim So Won, Lee Sung Hee, Kim Kyu-Earn, Kim Kyung Hwan, Lee Chun Geun, Elias Jack A, Lee Min Goo

Abstract excerpt

RATIONALE: Atopy or atopic syndrome is an allergic hypersensitivity subject to hereditary influences. Aberrant expression of chitinase 3-like 1 (CHI3L1), also known as YKL-40 or HC gp-39, is involved in the pathogenesis of inflammatory and allergic diseases. OBJECTIVES: The genetic contribution of CHI3L1 gene to atopic susceptibility was investigated using an integrated population genetic and molecular analysis....

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Identifiers

PMID: 19106306
DOI: 10.1164/rccm.200809-1422OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in the promoter region of chitinase 3-like 1 is associated with atopy.PMID 19106306Read ↗

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