Article
Association between risk of asthma and gene polymorphisms in CHI3L1 and CHIA: a systematic meta-analysis.
BMC pulmonary medicine - 12 Dec 2017
Zhu Yanting, Yan Xin, Zhai Cui, Yang Lan, Li Manxiang
Abstract excerpt
BACKGROUND: Previous studies have indicated that chitinase 3-like 1 (CHI3L1) gene rs4950928 polymorphism and acidic mammalian chitinase (AMCase or CHIA) gene rs10494132 polymorphism are associated with the risk of asthma. However, the results are inconsistent because of small sample size and varied ethnicity and age in studies. Therefore, a systematic meta-analysis was important to clarify the effect of CHI3L1...
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