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Article

Linkage analysis without defined pedigrees.

Genetic epidemiology - 1 Jul 2011

Day-Williams Aaron G, Blangero John, Dyer Thomas D, Lange Kenneth, Sobel Eric M

Abstract excerpt

The need to collect accurate and complete pedigree information has been a drawback of family-based linkage and association studies. Even in case-control studies, investigators should be aware of, and condition on, familial relationships. In single nucleotide polymorphism (SNP) genome scans, relatedness can be directly inferred from the genetic data rather than determined through interviews. Various methods of...

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Identifiers

PMID: 21465549
DOI: 10.1002/gepi.20584
PMCID: PMC3290352

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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