Article
The probabilistic determination of identity-by-descent sharing for pairs of relatives from pedigrees.
American journal of human genetics - 1 Nov 1990
Amos C I, Dawson D V, Elston R C
Abstract excerpt
Methods for detecting genetic linkage are more powerful when they fully use all of the data collected from pedigrees. We first discuss a method for obtaining the probability that a pedigree member has a given genotype, conditional on the phenotypes of his relatives. We then develop a rapid method...
Topics
- Alleles
- Female
- Genetic Linkage
- Genetic Markers
- Genotype
- Humans
- Male
- Pedigree
- Phenotype
- Probability
