Article
The probabilistic determination of identity-by-descent sharing for pairs of relatives from pedigrees.
American journal of human genetics - 1 Nov 1990
Amos C I, Dawson D V, Elston R C
Abstract excerpt
Methods for detecting genetic linkage are more powerful when they fully use all of the data collected from pedigrees. We first discuss a method for obtaining the probability that a pedigree member has a given genotype, conditional on the phenotypes of his relatives. We then develop a rapid method to obtain the conditional probabilities of identity-by-descent sharing of marker alleles for all related pairs of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
