Article
Fast Genome-Wide QTL Association Mapping on Pedigree and Population Data.
Genetic epidemiology - 1 Apr 2017
Zhou Hua, Blangero John, Dyer Thomas D, Chan Kei-Hang K, Lange Kenneth, Sobel Eric M
Abstract excerpt
Since most analysis software for genome-wide association studies (GWAS) currently exploit only unrelated individuals, there is a need for efficient applications that can handle general pedigree data or mixtures of both population and pedigree data. Even datasets thought to consist of only unrelated individuals may include cryptic relationships that can lead to false positives if not discovered and controlled for....
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