Article
Model-Free Linkage Analysis of a Binary Trait.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2017
Xu Wei, Ma Jin, Greenwood Celia M T, Paterson Andrew D, Bull Shelley B
Abstract excerpt
Genetic linkage analysis aims to detect chromosomal regions containing genetic variants that influence risk of specific inherited diseases. The presence of linkage is indicated when a disease or trait cosegregates through the families with genetic markers at a particular region of the genome. Two main types of genetic linkage analysis are in common use, namely model-based linkage analysis and model-free linkage...
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