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Mitochondrial fusion increases the mitochondrial DNA copy number in budding yeast.

Genes to cells : devoted to molecular & cellular mechanisms - 1 May 2011

Hori Akiko, Yoshida Minoru, Ling Feng

Abstract excerpt

Mitochondrial fusion plays an important role in mitochondrial DNA (mtDNA) maintenance, although the underlying mechanisms are unclear. In budding yeast, certain levels of reactive oxygen species (ROS) can promote recombination-mediated mtDNA replication, and mtDNA maintenance depends on the homologous DNA pairing protein Mhr1. Here, we show that the fusion of isolated yeast mitochondria, which can be monitored by...

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PMID: 21463454
DOI: 10.1111/j.1365-2443.2011.01504.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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