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Article

Evolution of the mitochondrial fusion-fission cycle and its role in aging.

Proceedings of the National Academy of Sciences of the United States of America - 21 Jun 2011

Kowald Axel, Kirkwood Tom B L

Abstract excerpt

Mitochondria are organelles of eukaryotic cells that contain their own genetic material and evolved from prokaryotic ancestors some 2 billion years ago. They are the main source of the cell's energy supply and are involved in such important processes as apoptosis, mitochondrial diseases, and aging. During recent years it also became apparent that mitochondria display a complex dynamical behavior of fission and...

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Identifiers

PMID: 21646529
DOI: 10.1073/pnas.1101604108
PMCID: PMC3121810

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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