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Article

Fusion and fission: interlinked processes critical for mitochondrial health.

Annual review of genetics - 1 Jan 2012

Chan David C

Abstract excerpt

Mitochondria are dynamic organelles that continually undergo fusion and fission. These opposing processes work in concert to maintain the shape, size, and number of mitochondria and their physiological function. Some of the major molecules mediating mitochondrial fusion and fission in mammals have been discovered, but the underlying molecular mechanisms are only partially unraveled. In particular, the cast of...

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PMID: 22934639
DOI: 10.1146/annurev-genet-110410-132529

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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