Article
Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast.
Molecular biology of the cell - 1 Sept 2006
Dürr Mark, Escobar-Henriques Mafalda, Merz Sandra, Geimer Stefan, Langer Thomas, Westermann Benedikt
Abstract excerpt
Mitochondria constantly fuse and divide to adapt organellar morphology to the cell's ever-changing physiological conditions. Little is known about the molecular mechanisms regulating mitochondrial dynamics. F-box proteins are subunits of both Skp1-Cullin-F-box (SCF) ubiquitin ligases and non-SCF complexes that regulate a large number of cellular processes. Here, we analyzed the roles of two yeast F-box proteins,...
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