Article
Nonredundant roles of mitochondria-associated F-box proteins Mfb1 and Mdm30 in maintenance of mitochondrial morphology in yeast.
Molecular biology of the cell - 1 Sept 2006
Dürr Mark, Escobar-Henriques Mafalda, Merz Sandra, Geimer Stefan, Langer Thomas, Westermann Benedikt
Abstract excerpt
Mitochondria constantly fuse and divide to adapt organellar morphology to the cell's ever-changing physiological conditions. Little is known about the molecular mechanisms regulating mitochondrial dynamics. F-box proteins are subunits of both Skp1-Cullin-F-box (SCF) ubiquitin ligases and non-SCF complexes that regulate a large number of cellular processes. Here, we analyzed the roles of two yeast F-box proteins,...
Topics
- Amino Acid Sequence
- F-Box Proteins
- GTP Phosphohydrolases
- Membrane Proteins
- Mitochondria
- Mitochondrial Proteins
- Molecular Sequence Data
- Phenotype
- Protein Binding
- Protein Subunits
- Protein Transport
- SKP Cullin F-Box Protein Ligases
- Saccharomyces cerevisiae