Article
Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52.
Genes & development - 1 Sept 1993
Milne G T, Weaver D T
Abstract excerpt
Saccharomyces cerevisiae rad52 mutants are characterized by severe defects in double-strand break (DSB) repair and recombination. In this study we have identified several regions of RAD52 that are required for these biological functions. We cloned and characterized a RAD52 homolog from Kluyveromyces lactis that partially complemented S. cerevisiae rad52 mutants while exhibiting negative dominance in wild-type...
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