Article
Dominant negative alleles of RAD52 reveal a DNA repair/recombination complex including Rad51 and Rad52.
Genes & development - 1 Sept 1993
Milne G T, Weaver D T
Abstract excerpt
Saccharomyces cerevisiae rad52 mutants are characterized by severe defects in double-strand break (DSB) repair and recombination. In this study we have identified several regions of RAD52 that are required for these biological functions. We cloned and characterized a RAD52 homolog from Kluyveromy...
Topics
- Alleles
- Amino Acid Sequence
- Base Sequence
- DNA Repair
- DNA, Fungal
- DNA, Single-Stranded
- DNA-Binding Proteins
- Fungal Proteins
- Genes, Dominant
- Genes, Fungal
- Genetic Complementation Test
- Kluyveromyces
- Mitosis
- Molecular Sequence Data
- Mutation
- Rad51 Recombinase
- Rad52 DNA Repair and Recombination Protein
- Recombination, Genetic