Article
Human and yeast Rad52 proteins promote DNA strand exchange.
Proceedings of the National Academy of Sciences of the United States of America - 29 Jun 2004
Bi Baoyuan, Rybalchenko Nataliya, Golub Efim I, Radding Charles M
Abstract excerpt
Studies of rad52 mutants in Saccharomyces cerevisiae have revealed a critical role of Rad52 protein in double-strand break repair and meiosis, and roles in both RAD51-dependent and -independent pathways of recombination. In vitro, both yeast and human Rad52 proteins play auxiliary roles with RPA in the action of Rad51. Rad52 also has annealing activity and promotes the formation of D-loops in superhelical DNA....
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
