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Article

Potential association of muscarinic receptor 3 gene variants with primary Sjogren's syndrome.

Annals of the rheumatic diseases - 1 Jul 2011

Appel Silke, Le Hellard Stephanie, Bruland Ove, Brun Johan G, Omdal Roald, Kristjansdottir Gudlaug, Theander Elke, Nordmark Gunnel, Kvarnström Marika, Eriksson Per, Rönnblom Lars, Wahren-Herlenius Marie, Jonsson Roland

Abstract excerpt

BACKGROUND: Primary Sjögren's syndrome (pSS) is characterised by a chronic inflammation of exocrine glands. Salivary gland infiltrates, however, do not correlate well with disease symptoms, and a primary role for the salivary gland parenchyma in disease development has been suggested. Specifically, dysfunction of exocrine pathways involving the muscarinic receptor 3 (CHRM3) has been indicated. OBJECTIVE: To...

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Source

Identifiers

PMID: 21450750
DOI: 10.1136/ard.2010.138966

Genes

CHRM3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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