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Article

D6S439 microsatellite identifies a new susceptibility region for primary Sjögren's syndrome.

The Journal of rheumatology - 1 Oct 2003

Anaya Juan-Manuel, Rivera Dora, Palacio Luis G, Arcos-Burgos Mauricio, Correa Paula A

Abstract excerpt

OBJECTIVE: To examine genetic variations in the region surrounding loci of the major histocompatibility complex, and to investigate the probable location of a new candidate region on the short arm of chromosome 6 predisposing to primary Sjögren's syndrome (SS). METHODS: We conducted an association study and positional candidate gene approach by microsatellite analysis. Five polymorphic microsatellite markers,...

Topics

Chromosomes, Human, Pair 6
DNA
DNA Primers
Female
Genetic Predisposition to Disease
HLA-DQ Antigens
HLA-DQ beta-Chains
HLA-DR Antigens
HLA-DRB1 Chains
Homozygote
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Linkage Disequilibrium

Male

Microsatellite Repeats

Middle Aged

Polymerase Chain Reaction

Polymorphism, Genetic

Sjogren's Syndrome

Source

Identifiers

PMID: 14528509

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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