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Article

Genetic associations to germinal centre formation in primary Sjogren's syndrome.

Annals of the rheumatic diseases - 1 Jun 2014

Reksten Tove Ragna, Johnsen Svein Joar Auglænd, Jonsson Malin Viktoria, Omdal Roald, Brun Johan G, Theander Elke, Eriksson Per, Wahren-Herlenius Marie, Jonsson Roland, Nordmark Gunnel

Abstract excerpt

BACKGROUND: Primary Sjögren's syndrome (pSS) is an autoimmune rheumatic disease mainly characterised by focal mononuclear cell infiltration in the salivary and lacrimal glands, and by the symptoms xerostomia and keratoconjunctivitis sicca. Germinal centre-like structures (GC) are found in the minor salivary glands of approximately 25% of patients. In this study, we aimed to assess genetic variations in pSS...

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Source

Identifiers

PMID: 23606706
DOI: 10.1136/annrheumdis-2012-202500

Genes

AICDA
BCL2
CARD8
CCL11
ICA1
IKBKE
PKN1
TANK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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