Article
No association of primary Sjögren's syndrome with Fcγ receptor gene variants.
Genes and immunity - 1 Jun 2013
Haldorsen K, Appel S, Le Hellard S, Bruland O, Brun J G, Omdal R, Kristjansdottir G, Theander E, Fernandes C P D, Kvarnström M, Eriksson P, Rönnblom L, Herlenius M W, Nordmark G, Jonsson R, Bolstad A I
Abstract excerpt
The genetic background of primary Sjögren's syndrome (pSS) is partly shared with systemic lupus erythematosus (SLE). Immunoglobulin G Fc receptors are important for clearance of immune complexes. Fcγ receptor variants and gene deletion have been found to confer SLE risk. In this study, four Fcγ receptor single-nucleotide polymorphisms (SNPs) and one copy number variation (CNV) were studied. Swedish and Norwegian...
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