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Article

Autoantibodies against muscarinic acetylcholine receptor M sub 3 sub in Sjogren rsquo s syndrome and corresponding mouse models

1 Jan 2018

Abstract excerpt

Muscarinic acetylcholine receptor M3 (M3R) is a GPCR on exocrine gland cells involved in fluid secretion. In the last two decades, evidence has been accumulated arguing for a role of autoantibodies (aab) against M3R in the development of Sjögren’s syndrome (SS). In this review, we provide an updated overview on this issue and critically discuss the relation between autoimmunity to M3R and SS pathogenesis....

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Identifiers

PMID: 29772545
DOI: 10.2741/4689

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