Article
Role of the Drosophila non-visual ß-arrestin kurtz in hedgehog signalling.
PLoS genetics - 1 Mar 2011
Molnar Cristina, Ruiz-Gómez Ana, Martín Mercedes, Rojo-Berciano Susana, Mayor Federico, de Celis Jose F
Abstract excerpt
The non-visual ß-arrestins are cytosolic proteins highly conserved across species that participate in a variety of signalling events, including plasma membrane receptor degradation, recycling, and signalling, and that can also act as scaffolding for kinases such as MAPK and Akt/PI3K. In Drosophila melanogaster, there is only a single non-visual ß-arrestin, encoded by kurtz, whose function is essential for...
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