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Article

Lgd regulates the activity of the BMP/Dpp signalling pathway during Drosophila oogenesis.

Development (Cambridge, England) - 1 Apr 2015

Morawa Kim Sara, Schneider Markus, Klein Thomas

Abstract excerpt

The tumour suppressor gene lethal (2) giant discs (lgd) is involved in endosomal trafficking of transmembrane proteins in Drosophila. Loss of function results in the ligand-independent activation of the Notch pathway in all imaginal disc cells and follicle cells. Analysis of lgd loss of function has largely been restricted to imaginal discs and suggests that no other signalling pathway is affected. The devotion...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 25804739
DOI: 10.1242/dev.112961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Lgd regulates the activity of the BMP/Dpp signalling pathway during Drosophila oogenesis.PMID 25804739Read ↗

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