Signaling through the G-protein-coupled receptor Rickets is important for polarity, detachment, and migration of the border cells in Drosophila.

doi:10.1016/j.ydbio.2016.04.017

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Article

Signaling through the G-protein-coupled receptor Rickets is important for polarity, detachment, and migration of the border cells in Drosophila.

Developmental biology - 15 Jun 2016

Anllo Lauren, Schüpbach Trudi

Abstract excerpt

Cell migration plays crucial roles during development. An excellent model to study coordinated cell movements is provided by the migration of border cell clusters within a developing Drosophila egg chamber. In a mutagenesis screen, we isolated two alleles of the gene rickets (rk) encoding a G-protein-coupled receptor. The rk alleles result in border cell migration defects in a significant fraction of egg...

Topics

Alleles
Animals
CCAAT-Enhancer-Binding Proteins
Cadherins
Cell Adhesion
Cell Movement
Cell Polarity
Drosophila Proteins
Drosophila melanogaster
Epithelial Cells
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Invertebrate Hormones

Mosaicism

Oogenesis

Ovary

Phenotype

RNA Interference

Receptors, G-Protein-Coupled

Source

Open in PubMed Open full text

Identifiers

PMID: 27130192
DOI: 10.1016/j.ydbio.2016.04.017
PMCID: PMC4887387

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