Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease.

Movement disorders : official journal of the Movement Disorder Society - 1 Apr 2011

Mata Ignacio F, Yearout Dora, Alvarez Victoria, Coto Eliecer, de Mena Lorena, Ribacoba Renee, Lorenzo-Betancor Oswaldo, Samaranch Lluis, Pastor Pau, Cervantes Sebastian, Infante Jon, Garcia-Gorostiaga Ines, Sierra Maria, Combarros Onofre, Snapinn Katherine W, Edwards Karen L, Zabetian Cyrus P

Abstract excerpt

Recent genome-wide association studies of Parkinson's disease have nominated 3 new susceptibility loci (PARK16-18) and confirmed 2 known risk genes (MAPT and SNCA) in populations of European ancestry. We sought to replicate these findings. We genotyped single-nucleotide polymorphisms in each of these genes/loci in 1445 Parkinson's disease patients and 1161 controls from northern Spain. Logistic regression was...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha-Synuclein
Share to DNA Replication

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to Logistic Models

Share to Odds Ratio

Share to Parkinson Disease

Share to tau Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 21425343
DOI: 10.1002/mds.23642
PMCID: PMC3082603

Genes

MAPT
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Replication of MAPT and SNCA, but not PARK16-18, as susceptibility genes for Parkinson's disease.PMID 21425343Read ↗

Genome-wide association study identifies common variants at four loci as genetic risk factors for Parkinson's disease.Semantic proximity Read ↗

Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies.Semantic proximity Read ↗

Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.Semantic proximity Read ↗

Genome-wide association study reveals genetic risk underlying Parkinson's disease.Semantic proximity Read ↗

Family-based association analysis of the MAPT gene in Parkinson disease.Semantic proximity Read ↗

Genome-wide association study confirms SNPs in SNCA and the MAPT region as common risk factors for Parkinson disease.Semantic proximity Read ↗

Novel Parkinson's disease risk loci identified through a meta-analysis of genome-wide association studies.Semantic proximity Read ↗

Genetic variability at the PARK16 locus.Semantic proximity Read ↗

Identification of novel risk loci, causal insights, and heritable risk for Parkinson's disease: a meta-analysis of genome-wide association studies.Semantic proximity Read ↗

Common variants in PARK loci and related genes and Parkinson's disease.Semantic proximity Read ↗

Supportive evidence for 11 loci from genome-wide association studies in Parkinson's disease.Semantic proximity Read ↗

Independent and joint effects of the MAPT and SNCA genes in Parkinson disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.