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Article

Genetic variability at the PARK16 locus.

European journal of human genetics : EJHG - 1 Dec 2010

Tucci Arianna, Nalls Mike A, Houlden Henry, Revesz Tamas, Singleton Andrew B, Wood Nicholas W, Hardy John, Paisán-Ruiz Coro

Abstract excerpt

Parkinson's disease (PD) is a complex neurodegenerative disease which is clinically heterogeneous and pathologically consists of loss of dopaminergic neurons in the substantia nigra and intracytoplasmic neuronal inclusions containing alpha-synuclein aggregations known as Lewy bodies. Although the majority of PD is idiopathic, pathogenic mutations in several mendelian genes have been successfully identified...

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Identifiers

PMID: 20683486
DOI: 10.1038/ejhg.2010.125
PMCID: PMC3002857

Genes

MAPT
SNCA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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