Article
Family-based association analysis of the MAPT gene in Parkinson disease.
Journal of applied genetics - 1 Jan 2010
Wang K S, Mullersman J E, Liu X F
Abstract excerpt
The MAPT gene has been shown to be associated with several neurodegenerative disorders, including forms of parkinsonism and Parkinson disease (PD), but the results reveal population differences. We investigated the association of 10 single-nucleotide polymorphisms (SNPs) in the region of MAPT on chromosome 17q21 with PD and age at onset, by using 443 discordant sib pairs in PD from a public dataset (Mayo-Perlegen...
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