Article
Expansion of regulatory T cells in aged mice following influenza infection.
Mechanisms of ageing and development - 1 Apr 2011
Williams-Bey Yolanda, Jiang Jiu, Murasko Donna M
Abstract excerpt
While it has been established that Treg cells can down-modulate an immune response, no study has addressed if the observed increase in Treg cells in aged mice is related to the decreased and delayed specific CD8 T cell responses seen following primary influenza infection. In this study, phenotypic characteristics and function of Treg cells were analyzed in young (4-6 months) and aged (18-22 months) mice prior to...
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