Article

Cellular Senescence is a Double-Edged Sword in Regulating Aged Immune Responses to Influenza

2023-04-11

Abstract excerpt

Clearance of senescent cells has demonstrated therapeutic potential in the context of chronic age-related diseases. Little is known, however, how clearing senescent cells affects the ability to respond to an acute infection and form quality immunological memory. We aimed to probe the effects of clearing senescent cells in aged mice on the immune response to influenza (flu) infection. We utilized a p16 trimodality...

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Literature Corpus work: 3cbc7514-3fab-531b-81d9-448b364080d5
DOI: 10.1101/2023.04.10.536027

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