Article
Intrinsic restriction activity by apolipoprotein B mRNA editing enzyme APOBEC1 against the mobility of autonomous retrotransposons.
Nucleic acids research - 1 Jul 2011
Ikeda Terumasa, Abd El Galil Khaled Hussein, Tokunaga Kenzo, Maeda Kazuhiko, Sata Tetsutaro, Sakaguchi Nobuo, Heidmann Thierry, Koito Atsushi
Abstract excerpt
The ability of mammalian cytidine deaminases encoded by the APOBEC3 (A3) genes to restrict a broad number of endogenous retroelements and exogenous retroviruses, including murine leukemia virus and human immunodeficiency virus (HIV)-1, is now well established. The RNA editing family member apolipoprotein B (apo B)-editing catalytic subunit 1 (APOBEC1; A1) from a variety of mammalian species, a protein involved in...
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