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Article

Retroelements versus APOBEC3 family members: No great escape from the magnificent seven

1 Jan 2012

Abstract excerpt

Retroelements comprise a large and successful family of transposable genetic elements that, through intensive infiltration, have shaped the genomes of humans and other mammals over millions of years. In fact, retrotransposons now account for approximately 45% of the human genome. Because of their genomic mobility called retrotransposition, some retroelements can cause genetic diseases; such retrotransposition...

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PMID: 22912627
DOI: 10.3389/fmicb.2012.00275

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