Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Role of APOBECs in Viral Replication

30 Nov 2020

Abstract excerpt

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) proteins are a diverse and evolutionarily conserved family of cytidine deaminases that provide a variety of functions from tissue-specific gene expression and immunoglobulin diversity to control of viruses and retrotransposons. APOBEC family expansion has been documented among mammalian species, suggesting a powerful selection for their...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytomegalovirus and herpesvirus research
Share to HIV/AIDS drug development and treatment
Share to HIV Research and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33266042
DOI: 10.3390/microorganisms8121899

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Role of APOBECs in Viral ReplicationPMID 33266042Read ↗

APOBEC3 Interference during Replication of Viral Genomes.Semantic proximity Read ↗

APOBECs and HerpesvirusesSemantic proximity Read ↗

Interactions of host APOBEC3 restriction factors with HIV-1 in vivo: implications for therapeuticsSemantic proximity Read ↗

Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them AllSemantic proximity Read ↗

The APOBEC3 Cytidine Deaminases: An Innate Defensive Network Opposing Exogenous Retroviruses and Endogenous RetroelementsSemantic proximity Read ↗

Human APOBEC3 Variations and Viral InfectionSemantic proximity Read ↗

The role of cytidine deaminases on innate immune responses against human viral infections.Semantic proximity Read ↗

Role of the single deaminase domain APOBEC3A in virus restriction, retrotransposition, DNA damage and cancerSemantic proximity Read ↗

Cytidine Deaminases as a Weapon Against Retroviruses and a New Target for Antiviral TherapySemantic proximity Read ↗

APOBEC3 family proteins as drivers of virus evolutionSemantic proximity Read ↗

APOBEC-mediated editing of viral RNA.Semantic proximity Read ↗

A conflict of interest: the evolutionary arms race between mammalian APOBEC3 and lentiviral VifSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.