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Article

Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity.

Scientific reports - 21 Apr 2017

Ikeda Terumasa, Shimoda Mayuko, Ebrahimi Diako, VandeBerg John L, Harris Reuben S, Koito Atsushi, Maeda Kazuhiko

Abstract excerpt

APOBEC3s (A3s) are single-stranded DNA cytosine deaminases that provide innate immune defences against retroviruses and mobile elements. A3s are specific to eutherian mammals because no direct homologs exist at the syntenic genomic locus in metatherian (marsupial) or prototherian (monotreme) mammals. However, the A3s in these species have the likely evolutionary precursors, the antibody gene deaminase AID and the...

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Identifiers

PMID: 28429755
DOI: 10.1038/srep46719
PMCID: PMC5399452

Genes

APOBEC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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