Article
The effect of the brain-type natriuretic peptide single-nucleotide polymorphism rs198389 on test characteristics of common assays.
Mayo Clinic proceedings - 1 Mar 2011
Costello-Boerrigter Lisa C, Boerrigter Guido, Ameenuddin Syed, Mahoney Douglas W, Slusser Joshua P, Heublein Denise M, Redfield Margaret M, Rodeheffer Richard J, Olson Timothy M, Burnett John C
Abstract excerpt
OBJECTIVE: To assess in a US general adult population the effect of the functional single-nucleotide polymorphism rs198389 in the promoter region of the gene of brain-type natriuretic peptide (BNP) on 3 commonly used BNP assays, clinical phenotype, disease prevalence, overall survival, and diagnostic test characteristics of BNP as a biomarker. PATIENTS AND METHODS: We genotyped for rs198389 in a random sample of...
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