Article
A functional genetic variant (N521D) in natriuretic peptide receptor 3 is associated with diastolic dysfunction: the prevalence of asymptomatic ventricular dysfunction study.
PloS one - 1 Jan 2014
Pereira Naveen L, Redfield Margaret M, Scott Christopher, Tosakulwong Nirubol, Olson Timothy M, Bailey Kent R, Rodeheffer Richard J, Burnett John C
Abstract excerpt
OBJECTIVES: To evaluate the impact of a functional genetic variant in the natriuretic peptide clearance receptor, NPR3, on circulating natriuretic peptides (NPs) and myocardial structure and function in the general community. BACKGROUND: NPR3 plays an important role in the clearance of NPs and th...
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