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Article

Association Analyses Between the NPPB:rs198389 Gene Polymorphism, NT-proBNP Serum Concentrations and Phenotypic Features in Patients with Heart Failure.

Genes - 14 Apr 2026

Gorący-Rosik Anna, Rosik Jakub, Lewandowska Klaudyna, Gorący Iwona, Ciechanowicz Andrzej

Abstract excerpt

BACKGROUND: Heart failure (HF) is a complex disease and one of the major causes of morbidity and mortality in the world. Increased B-type natriuretic peptide (BNP) levels have been associated with HF. The NPPB:rs198389 (c.-381T > C) promoter polymorphism has been found to modulate BNP levels. AIM: To investigate possible associations among the NPPB:rs198389 polymorphism, N-terminal pro-BNP (NT-proBNP)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Promoter Regions, Genetic

Source

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Identifiers

PMID: 42074572
DOI: 10.3390/genes17040454
PMCID: PMC13116900

Genes

NPPB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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