A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community.

doi:10.1016/j.jacc.2011.05.011

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community.

Journal of the American College of Cardiology - 2 Aug 2011

Cannone Valentina, Boerrigter Guido, Cataliotti Alessandro, Costello-Boerrigter Lisa C, Olson Timothy M, McKie Paul M, Heublein Denise M, Lahr Brian D, Bailey Kent R, Averna Maurizio, Redfield Margaret M, Rodeheffer Richard J, Burnett John C

Abstract excerpt

OBJECTIVES: We sought to define the cardiometabolic phenotype associated with rs5068, a genetic variant of the atrial natriuretic peptide (ANP) gene. BACKGROUND: The ANP and B-type natriuretic peptide play an important role in cardiorenal homeostasis but also exert metabolic actions. METHODS: We genotyped 1,608 randomly selected residents from Olmsted County, Minnesota. Subjects were well-characterized. RESULTS:...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Atrial Natriuretic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Blood Pressure

Share to Body Mass Index

Share to Echocardiography, Doppler

Share to Homeostasis

Share to Natriuretic Peptide, Brain

Share to Protein Structure, Tertiary

Share to Random Allocation

Source

Open in PubMed Open full text

Identifiers

PMID: 21798427
DOI: 10.1016/j.jacc.2011.05.011
PMCID: PMC3188554

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A genetic variant of the atrial natriuretic peptide gene is associated with cardiometabolic protection in the general community.PMID 21798427Read ↗

Sex-based differences in metabolic protection by the ANP genetic variant rs5068 in the general population.Semantic proximity Read ↗

The atrial natriuretic peptide genetic variant rs5068 is associated with a favorable cardiometabolic phenotype in a Mediterranean population.Semantic proximity Read ↗

A favorable cardiometabolic profile is associated with the G allele of the genetic variant rs5068 in African Americans: The Multi-Ethnic Study of Atherosclerosis (MESA).Semantic proximity Read ↗

A genetic variant of the atrial natriuretic peptide gene is associated with left ventricular hypertrophy in a non-diabetic population--the Malmö preventive project study.Semantic proximity Read ↗

Atrial natriuretic peptide genetic variant rs5065 and risk for cardiovascular disease in the general community: a 9-year follow-up study.Semantic proximity Read ↗

Association of genetic variation in the natriuretic peptide system with cardiovascular outcomes.Semantic proximity Read ↗

Influence of rs5065 atrial natriuretic peptide gene variant on coronary artery disease.Semantic proximity Read ↗

Association between ADRA1A gene and the metabolic syndrome: candidate genes and functional counterpart in the PAMELA population.Semantic proximity Read ↗

An NPPB Promoter Polymorphism Associated With Elevated N-Terminal pro-B-Type Natriuretic Peptide and Lower Blood Pressure, Hypertension, and Mortality.Semantic proximity Read ↗

Association of common variants in NPPA and NPPB with circulating natriuretic peptides and blood pressure.Semantic proximity Read ↗

Corin gene minor allele defined by 2 missense mutations is common in blacks and associated with high blood pressure and hypertension.Semantic proximity Read ↗

Genome-Wide Association Study Implicates Atrial Natriuretic Peptide Rather Than B-Type Natriuretic Peptide in the Regulation of Blood Pressure in the General Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.