Article
Common genetic variants of the natriuretic peptide gene locus are not associated with heart failure risk in participants in the EPIC-Norfolk study.
European journal of heart failure - 1 Jun 2013
Pfister Roman, Luben Robert N, Khaw Kay-Tee, Wareham Nick J
Abstract excerpt
AIMS: BNP has important effects on haemodynamics and myocardial remodelling which are protective from development and progression of heart failure. The aim of this study was to examine whether three common genetic variants (rs198389, rs5068, and rs198358) within or adjacent to the BNP gene locus which were shown to be associated with BNP blood levels are associated with risk of heart failure in the pospective...
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