Article
Genetic variation in the B-type natiuretic peptide pathway affects BNP levels.
Cardiovascular drugs and therapy - 1 Feb 2007
Lanfear David E, Stolker Joshua M, Marsh Sharon, Rich Michael W, McLeod Howard L
Abstract excerpt
PURPOSE: The importance of B-type natriuretic peptide (BNP) as a diagnostic and therapeutic modality in cardiovascular disease is well known. BNP levels correlate clinical and physiologic characteristics, as well as outcomes. We sought to investigate the influence of BNP pathway genetic variation on BNP levels after adjustment for clinical/physiologic factors. MATERIALS AND METHODS: DNA was extracted from 147...
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