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Article

Genetic polymorphism of the type A human natriuretic peptide receptor (NPR-A) gene contributes to the interindividual variability in the BNP system.

European journal of heart failure - 1 May 2008

Weber Michael, Burian Maria, Dragutinovic Ivana, Moellmann Helge, Nef Holger, Elsaesser Albrecht, Mitrovic Veselin, Hamm Christian, Geisslinger Gerd

Abstract excerpt

AIMS: To analyse the contribution of recently described genetic polymorphisms in the human natriuretic peptide receptor (NPR-A) to the interindividual variability in the BNP system. METHODS AND RESULTS: We evaluated NT-proBNP in 402 subjects, including healthy controls (n=93), patients with acute coronary syndrome (n=194) and heart failure (n=115). Three polymorphic sites encoding six common haplotypes of the...

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Identifiers

PMID: 18436476
DOI: 10.1016/j.ejheart.2008.03.009

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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