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Article

IKKε regulates cell elongation through recycling endosome shuttling.

Developmental cell - 15 Feb 2011

Otani Tetsuhisa, Oshima Kenzi, Onishi Sachiko, Takeda Michiko, Shinmyozu Kaori, Yonemura Shigenobu, Hayashi Shigeo

Abstract excerpt

IKK-related kinases are key regulators of innate immunity and oncogenesis. While their effects on transcription are well characterized, their cytoplasmic functions remain poorly understood. Drosophila IKK-related kinase, IKKɛ, regulates cytoskeletal organization and cell elongation. Here, we demonstrate that IKKɛ is activated locally at the tip of growing mechanosensory bristles and regulates the rapid shuttling...

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PMID: 21316589
DOI: 10.1016/j.devcel.2011.02.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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