Article

Distinct Rab11-associated membrane trafficking pathways bidirectionally control neuronal extracellular vesicle cargo traffic

2026-02-25

Abstract excerpt

Neuronal extracellular vesicles (EVs) are released from synapses, and play roles in cellular communication, proteostasis, and the spread of toxic proteins in disease. The small GTPase Rab11 is required to maintain a reservoir of EV cargoes at presynaptic terminals, but how its diverse effector proteins contribute to this function and where Rab11 acts in neurons remains unclear. Using Drosophila motor neurons as a...

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Literature Corpus work: 1400ba8b-e2e1-5141-8f82-4d60ad014226
DOI: 10.64898/2026.02.25.708063

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