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The kinesin KIF3AC recycles endocytosed integrin to polarize adhesion formation towards the leading edge

2024-12-12

Abstract excerpt

The recycling of integrin endocytosed during focal adhesion (FA) disassembly is critical for cell migration and contributes to the polarized formation of new FAs toward the leading edge. How this occurs is unclear. Here, we sought to identify the kinesin motor protein(s) that is involved in recycling endocytosed integrin back to the plasma membrane. We show that the kinesin-2 heterodimer, KIF3AC and the Rab11 adap...

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Identifiers and source

Literature Corpus work
12671f1e-1e15-5a00-b57b-130eb519784b
DOI
10.1101/2024.12.09.627580
Open publication

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The kinesin KIF3AC recycles endocytosed integrin to polarize adhesion formation towards the leading edgeDOI 10.1101/2024.12.09.627580
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