Article
Nuf, a Rab11 effector, maintains cytokinetic furrow integrity by promoting local actin polymerization.
The Journal of cell biology - 28 Jul 2008
Cao Jian, Albertson Roger, Riggs Blake, Field Christine M, Sullivan William
Abstract excerpt
Plasma membrane ingression during cytokinesis involves both actin remodeling and vesicle-mediated membrane addition. Vesicle-based membrane delivery from the recycling endosome (RE) has an essential but ill-defined involvement in cytokinesis. In the Drosophila melanogaster early embryo, Nuf (Nuclear fallout), a Rab11 effector which is essential for RE function, is required for F-actin and membrane integrity...
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