Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Cell Polarity Regulates Biased Myosin Activity and Dynamics during Asymmetric Cell Division via Drosophila Rho Kinase and Protein Kinase N.

Developmental cell - 24 Jul 2017

Tsankova Anna, Pham Tri Thanh, Garcia David Salvador, Otte Fabian, Cabernard Clemens

Abstract excerpt

Cell and tissue morphogenesis depends on the correct regulation of non-muscle Myosin II, but how this motor protein is spatiotemporally controlled is incompletely understood. Here, we show that in asymmetrically dividing Drosophila neural stem cells, cell intrinsic polarity cues provide spatial and temporal information to regulate biased Myosin activity. Using live cell imaging and a genetically encoded Myosin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anaphase
Share to Cell Polarity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cell Shape

Share to Drosophila Proteins

Share to Myosins

Share to Protein Kinase C

Share to Protein Transport

Share to rho-Associated Kinases

Source

Identifiers

PMID: 28712722
DOI: 10.1016/j.devcel.2017.06.012

Genes

NEB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Cell Polarity Regulates Biased Myosin Activity and Dynamics during Asymmetric Cell Division via Drosophila Rho Kinase and Protein Kinase N.PMID 28712722Read ↗

An apical MRCK-driven morphogenetic pathway controls epithelial polarity.Semantic proximity Read ↗

Apical Constriction Reversal upon Mitotic Entry Underlies Different Morphogenetic Outcomes of Cell Division.Semantic proximity Read ↗

CGEF-1 and CHIN-1 regulate CDC-42 activity during asymmetric division in the Caenorhabditis elegans embryo.Semantic proximity Read ↗

A mouse homologue of Drosophila pins can asymmetrically localize and substitute for pins function in Drosophila neuroblasts.Semantic proximity Read ↗

RAB-5 controls the cortical organization and dynamics of PAR proteins to maintain C. elegans early embryonic polarity.Semantic proximity Read ↗

Bazooka provides an apical cue for Inscuteable localization in Drosophila neuroblasts.Semantic proximity Read ↗

Planar polarization of the denticle field in the Drosophila embryo: roles for Myosin II (zipper) and fringe.Semantic proximity Read ↗

Cleavage furrow-directed cortical flows bias mechanochemical pathways for PAR polarization in the <i>C. elegans</i> germ lineageSemantic proximity Read ↗

Cortical forces and CDC-42 control clustering of PAR proteins for Caenorhabditis elegans embryonic polarization.Semantic proximity Read ↗

cdc2 links the Drosophila cell cycle and asymmetric division machineries.Semantic proximity Read ↗

PAR-4/LKB1 mobilizes nonmuscle myosin through anillin to regulate C. elegans embryonic polarization and cytokinesis.Semantic proximity Read ↗

Bazooka recruits Inscuteable to orient asymmetric cell divisions in Drosophila neuroblasts.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.