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Article

The Drosophila FHOD1-like formin Knittrig acts through Rok to promote stress fiber formation and directed macrophage migration during the cellular immune response.

Development (Cambridge, England) - 1 Mar 2014

Lammel Uwe, Bechtold Meike, Risse Benjamin, Berh Dimitri, Fleige Astrid, Bunse Ingrid, Jiang Xiaoyi, Klämbt Christian, Bogdan Sven

Abstract excerpt

A tight spatiotemporal control of actin polymerization is important for many cellular processes that shape cells into a multicellular organism. The formation of unbranched F-actin is induced by several members of the formin family. Drosophila encodes six formin genes, representing six of the seven known mammalian subclasses. Knittrig, the Drosophila homolog of mammalian FHOD1, is specifically expressed in the...

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Source

Identifiers

PMID: 24553290
DOI: 10.1242/dev.101352

Genes

FHOD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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