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Article

Concordance of CCR5 genotypes that influence cell-mediated immunity and HIV-1 disease progression rates.

The Journal of infectious diseases - 15 Jan 2011

Catano Gabriel, Chykarenko Zoya A, Mangano Andrea, Anaya J-M, He Weijing, Smith Alison, Bologna Rosa, Sen Luisa, Clark Robert A, Lloyd Andrew, Shostakovich-Koretskaya Ludmila, Ahuja Sunil K

Abstract excerpt

We used cutaneous delayed-type hypersensitivity responses, a powerful in vivo measure of cell-mediated immunity, to evaluate the relationships among cell-mediated immunity, AIDS, and polymorphisms in CCR5, the HIV-1 coreceptor. There was high concordance between CCR5 polymorphisms and haplotype pairs that influenced delayed-type hypersensitivity responses in healthy persons and HIV disease progression. In the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21288827
DOI: 10.1093/infdis/jiq023
PMCID: PMC3071050

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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