Article
Distinctive effects of CCR5, CCR2, and SDF1 genetic polymorphisms in AIDS progression.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association - 1 Dec 1998
Hendel H, Hénon N, Lebuanec H, Lachgar A, Poncelet H, Caillat-Zucman S, Winkler C A, Smith M W, Kenefic L, O'Brien S, Lu W, Andrieu J M, Zagury D, Schächter F, Rappaport J, Zagury J F
Abstract excerpt
The Genetics of Resistance to Infection by HIV-1 (GRIV) cohort represents 200 nonprogressor/slow-progressor (Slowprog) and 90 fast-progressor (Fastprog) HIV-1-infected patients. Using this unique assembly, we performed genetic studies on three recently discovered polymorphisms of CCR5, CCR2, and...
Topics
- Acquired Immunodeficiency Syndrome
- CD4-CD8 Ratio
- Chemokine CXCL12
- Chemokines, CXC
- Cohort Studies
- Disease Progression
- France
- Genotype
- HIV Infections
- HIV-1
- Humans
- Immunity, Innate
- Leukocyte Count