Article
Host genetic variation and HIV disease: from mapping to mechanism.
Immunogenetics - 1 Aug 2017
Naranbhai Vivek, Carrington Mary
Abstract excerpt
This review aims to provide a summary of current knowledge of host genetic effects on human immunodeficiency virus (HIV) disease. Mapping of simple single nucleotide polymorphisms (SNP) has been largely successful in HIV, but more complex genetic associations involving haplotypic or epigenetic variation, for example, remain elusive. Mechanistic insights explaining SNP associations are incomplete, but continue to...
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