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Host genetic variants regulates CCR5 expression on immune cells: a study in people living with HIV and healthy controls

2022-06-20

Abstract excerpt

C-C chemokine receptor 5 (CCR5) is the main HIV co-receptor affecting susceptibility and disease course. Quantitative trait loci (QTL) mapping analysis was performed to assess genetic variants associated with CCR5 expression on circulating immune cells in 209 PLHIV using ART and 304 healthy controls, all of Western European ancestry. The proportions of CCR5 positive cells and CCR5 mean fluorescence intensity (MFI)...

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Literature Corpus work
feb618e7-e9aa-5333-b766-7420e8ef2de7
DOI
10.1101/2022.06.19.496757
Open publication

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Host genetic variants regulates CCR5 expression on immune cells: a study in people living with HIV and healthy controlsDOI 10.1101/2022.06.19.496757
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