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Article

Beyond HIV infection: Neglected and varied impacts of CCR5 and CCR5Δ32 on viral diseases.

Virus research - 1 Sept 2020

Ellwanger Joel Henrique, Kulmann-Leal Bruna, Kaminski Valéria de Lima, Rodrigues Andressa Gonçalves, Bragatte Marcelo Alves de Souza, Chies José Artur Bogo

Abstract excerpt

The interactions between chemokine receptors and their ligands may affect susceptibility to infectious diseases as well as their clinical manifestations. These interactions mediate both the traffic of inflammatory cells and virus-associated immune responses. In the context of viral infections, the human C-C chemokine receptor type 5 (CCR5) receives great attention from the scientific community due to its role as...

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Identifiers

PMID: 32479976
DOI: 10.1016/j.virusres.2020.198040
PMCID: PMC7260533

Genes

CCR5

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