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Article

Global analysis of the impact of environmental perturbation on cis-regulation of gene expression.

PLoS genetics - 20 Jan 2011

Grundberg Elin, Adoue Veronique, Kwan Tony, Ge Bing, Duan Qing Ling, Lam Kevin C L, Koka Vonda, Kindmark Andreas, Weiss Scott T, Tantisira Kelan, Mallmin Hans, Raby Benjamin A, Nilsson Olle, Pastinen Tomi

Abstract excerpt

Genetic variants altering cis-regulation of normal gene expression (cis-eQTLs) have been extensively mapped in human cells and tissues, but the extent by which controlled, environmental perturbation influences cis-eQTLs is unclear. We carried out large-scale induction experiments using primary human bone cells derived from unrelated donors of Swedish origin treated with 18 different stimuli (7 treatments and 2...

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Identifiers

PMID: 21283786
DOI: 10.1371/journal.pgen.1001279
PMCID: PMC3024267

Genes

MYO6
TNC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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