Article

Disease-associated loci share properties with response eQTLs under common environmental exposures

2025-05-04

Abstract excerpt

Many of the genetic loci associated with disease are expected to have context-dependent regulatory effects that are underrepresented in the transcriptomes of healthy, steady-state adult tissues. To understand gene regulation across diverse environmental conditions and cellular contexts, we treated a broad array of human cell types with three environmental exposures in vitro . With single-cell RNA-sequencing data...

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Literature Corpus work: b40b7e0c-f5af-5d2c-bd13-7a49dd0ed82a
DOI: 10.1101/2025.04.30.651602

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