Article

Interactions between genetic variation and cellular environment in skeletal muscle gene expression

2017-02-03

Abstract excerpt

From whole organisms to individual cells, responses to environmental conditions are influenced by genetic makeup, where the effect of genetic variation on a trait depends on the environmental context. RNA-sequencing quantifies gene expression as a molecular trait, and is capable of capturing both genetic and environmental effects. In this study, we explore opportunities of using allele-specific expression (ASE) to...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 9ddfb638-38ce-5cd1-8f2b-3d8847c2991f
DOI: 10.1101/105429

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Interactions between genetic variation and cellular environment in skeletal muscle gene expressionDOI 10.1101/105429Read

Interactions between genetic variation and cellular environment in skeletal muscle gene expression.Semantic proximity Read

Allele-specific expression reveals interactions between genetic variation and environmentSemantic proximity Read

Transcriptome Sequencing Reveals Widespread Gene-Gene and Gene-Environment InteractionsSemantic proximity Read

Local genetic effects on gene expression across 44 human tissuesSemantic proximity Read

Allele-specific expression reveals interactions between genetic variation and environment.Semantic proximity Read

BMI-genome interactions regulate global gene expression with emphasis in brain and gut.Semantic proximity Read

High-throughput allele-specific expression across 250 environmental conditions.Semantic proximity Read

Gene-gene and gene-environment interactions detected by transcriptome sequence analysis in twins.Semantic proximity Read

Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression.Semantic proximity Read

Genetic effects on gene expression across human tissues.Semantic proximity Read

ASEP: Gene-based detection of allele-specific expression across individuals in a population by RNA sequencing.Semantic proximity Read

Analysis of the impact of genetic variation on human gene expression.Semantic proximity Read